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These processes include upregulation of genes responsible for collagen type I and type III production, stimulation of elastin synthesis, and enhancement of glycosaminoglycan formation

Moreover, the increase in GSH levels induced by Nrf2 activation prevents the p75 NTR -mediated apoptosis of neurons in vitro (Vargas et al., 2006)

In the TME, high levels of ROS lead to cellular damage, disrupting the balance of mitochondrial dynamics and resulting in mitochondrial fragmentation and dysfunction

BPC-157, along with Human gastric juice, has demonstrated gastroprotective properties by promoting the healing of damaged gastric and intestinal tissues, reducing inflammation, and preventing ulcer formation in the stomach

doi: 10.1093/brain/awac016 142 LuchicchiA.HartB.FrigerioI.van DamA